Last update
3/2/2026
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size:  3 Tablets
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
100 mg
111%
Calcium (from Calcium Phosphate, Calcium Stearate)
30 mg
2%
L-Lysine (from L-Lysine Hydrochloride)
1.5 g
Garlic Bulb (deodorized)
200 mg
Echinacea purpurea Aerial Parts Extract 4:1 
100 mg
Propolis 
25 mg
Licorice Root Extract 4:1
15 mg
📅 Last updated:

Top Medical Research Studies

9
RCI001 shows promise for Sjögren syndrome
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.

After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
Read More
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
Read More

Most Useful Reviews

9
Quick recovery support
4 people found this helpful
This is an excellent natural immunity stimulator! I’ve taken it several times when unwell and felt better within days. I even gave half a tablet to my 5-year-old child, who coped well. I'd recommend it without hesitation; you won't regret it!
Read More
9
Prevents infections
3 people found this helpful
I have several autoimmune disorders, and my rheumatologist recommended starting a daily L-Lysine regimen during cold and flu season to fend off the frequent infections we face on immunosuppressants. Normally, I endure multiple severe colds or even the flu by this time, but since taking this supplement for the last four months, I have been perfectly fine! I encourage all the patients in my clinic to try this! L-Lysine isn’t just for herpes; it also inhibits the replication of viruses, such as colds and flu! Use it to prevent illness or at the first signs of an infection to reduce duration and severity.
Read More
7.5
Trustworthy immune booster
3 people found this helpful
I’ve ordered this complex again, as it's very effective! When I feel unwell, I take one daily, and within 2-3 days, I'm back to normal. I continued for four more days to enhance my immune system, and it worked wonders for my husband too!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
  • All Researches
9
RCI001 shows promise for Sjögren syndrome
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.

After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
Read More
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
Read More

User Reviews

USERS' SCORE
Good
Based on 7 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Quick recovery support
4 people found this helpful
This is an excellent natural immunity stimulator! I’ve taken it several times when unwell and felt better within days. I even gave half a tablet to my 5-year-old child, who coped well. I'd recommend it without hesitation; you won't regret it!
Read More
9
Prevents infections
3 people found this helpful
I have several autoimmune disorders, and my rheumatologist recommended starting a daily L-Lysine regimen during cold and flu season to fend off the frequent infections we face on immunosuppressants. Normally, I endure multiple severe colds or even the flu by this time, but since taking this supplement for the last four months, I have been perfectly fine! I encourage all the patients in my clinic to try this! L-Lysine isn’t just for herpes; it also inhibits the replication of viruses, such as colds and flu! Use it to prevent illness or at the first signs of an infection to reduce duration and severity.
Read More
7.5
Trustworthy immune booster
3 people found this helpful
I’ve ordered this complex again, as it's very effective! When I feel unwell, I take one daily, and within 2-3 days, I'm back to normal. I continued for four more days to enhance my immune system, and it worked wonders for my husband too!
Read More
9
Supportive blend
1 people found this helpful
I ordered these to support my immunity during autumn. Having taken them previously without falling ill, I appreciate the beneficial ingredients like Vitamin C and lysine.
Read More
9
Effective immunity support
I regularly order this supplement to boost my immune system, especially in autumn and winter. It's proven effective, and the composition is impressive.
Read More

Frequently Asked Questions

9
Supportive blend
1 people found this helpful
I ordered these to support my immunity during autumn. Having taken them previously without falling ill, I appreciate the beneficial ingredients like Vitamin C and lysine.
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
9
RCI001 shows promise for Sjögren syndrome
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.

After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.

References

  1. Mishra R, Agarwal P, Sharma A, Mittal M, Gulati P, et al. Plant-derived Cyclotides in Immunomodulation and their Therapeutic Potential. Protein Pept Lett. 2025. 10.2174/0109298665364479250214101422
  2. Kang H, Jung YH, Moon J, Ryu JS, Yoon CH, et al. Efficacy of RCI001 as a Therapeutic Candidate in a Primary Sjögren Syndrome Mouse Model. Cornea. 2025;44:226. 10.1097/ICO.0000000000003696
Data last updated:
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